
PE-backed Brii Bioscience pursues Hong Kong listing
Brii Biosciences, a three-year-old Chinese biotech start-up that has raised approximately $415 million in private funding from the likes of Sequoia Capital China, Boyu Capital, and Yunfeng Capital, has filed for a Hong Kong IPO.
The company began operations in May 2018 after securing exclusive Greater China rights to four assets from US-based Vir Biotechnology. Partnerships were also announced with Alibaba Group to develop new medicines with AliHealth, as well as with WuXi AppTec and WuXi Biologics to cooperate on R&D.
Around the same time, Sequoia, Boyu and Yunfeng were joined by Arch Ventures Partners, 6 Dimensions Capital, and Blue Pool Capital in Series A and B rounds together worth $260 million. Yunfeng is a private equity firm established by Alibaba founder Jack Ma, while Blue Pool is said to manage the family money of Ma and Joe Tsai, Alibaba’s executive vice-chairman.
Last month, Invesco led a $155 million round – described as a Series C – for Brii, with participation from GIC and Lake Bleu Capital. The post-money valuation was $1.45 billion, up from $198 million in the Series A.
The company has added to its portfolio and now boasts a pipeline of more than 10 innovative product candidates. They include treatments for hepatitis B, HIV, tuberculosis, bacterial infections, COVID-19, paranoid personality disorder, and depression. The hepatitis B and COVID-19 candidates are the most advanced. They are in phase-two clinical trials in China and globally, respectively.
Brii generated RMB84.6 million ($12.9 million) in income for 2020, up from RMB20.3 million the previous year. Its net loss widened from RMB535.3 million to RMB1.17 billion, largely due to a 10-fold increase in R&D spending. It is listing under provisions that allow pre-revenue biotech companies to go public in Hong Kong.
Boyu is the largest shareholder in Brii with 18.53%, closely followed by 6 Dimensions and Arch with 17.8% apiece, according to the IPO prospectus. Sequoia and Yunfeng each own 9.72%, while Vir has 5.68%, Invesco has 3.64%, Blue Pool has 3.02%, and GIC has 2.18%. Zhi Hong, Brii’s co-founder and CEO, holds 5.45%.
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